How MultiDez Works
MultiDez, when applied properly, becomes bonded to the surface and forms a durable technology coating which is highly resistant to microbial attack.
Unlike conventional antimicrobials, MultiDez, once dried, does not emit gas, leach, diffuse, migrate or otherwise leave the surface to which it has been applied. The result is a surface with a long lasting protection against, fungi, bacteria, moulds & viruses.
Antimicrobials can be divided into two major categories; bound and unbound. These terms refer to whether or not the antimicrobial has the capacity to molecularly bond to the surface to which it is applied.
PHMG is a long chained polymer. The bactericidal effect of the molecule is based on the positive charge of the guanidine group located in each monomer. The mechanism of action is:
Adsorption: The negative charge on the bacterial cell wall attracts the positively charged N+ ion of the PHMG molecule.
On the surface of the bacterial cell PHMG forms a molecular net that inhibits the proteins of the cellular membrane changing the osmotic pressure and stability of the cell.
PHMG diffuses through the cellular membrane and binds to the cytoplasmic membrane forming a complex with the phospholipid molecules of the lipid bilayer that is more stable than the structure of the membrane.
The structure of the membrane is broken, the cytoplasmic components are released to the environment and the cell dies.
In any time of the mechanism of action PHMG does not come in contact with the genetic material, DNA or RNA, therefore it is very hard for the bacterial cells to generate any resistance to the molecule.

The MultiDez molecule

Illustration of the polymeric nature of MultiDez


